Our lab is interested in motor neuron development
​and disease

Our lab uses the specific strengths of C. elegans and mice to reveal the gene regulatory mechanisms that control motor neuron development and function. We employ novel methodology, such as whole genome sequencing, CRISPR genome editing, ATAC-seq and cell type-specific transcriptome profiling. Our laboratory aims to systematically test whether the function of the gene regulatory factors we discover in C. elegans is conserved across phylogeny using mouse genetics and novel genomic approaches.